Skincare University

Prebiotics, probiotics, and postbiotics

LEVEL 3
The World of Fermented Ingredients

LEVEL 3 The World of Fermented Ingredients

Microbiome-related ingredients in skincare fall into three major categories. Understanding their differences will significantly improve your product selection.

Prebiotics — "food" for beneficial bacteria

Prebiotics are ingredients that serve as nutrition for the skin's resident bacteria (beneficial flora). Common examples include inulin, fructo-oligosaccharides, and alpha-glucan oligosaccharide. By creating an environment that promotes the growth of beneficial bacteria, they indirectly support skin health.

Probiotics — living microorganisms themselves

Probiotics involve applying live microorganisms directly to the skin. While widely used for gut health, stability challenges present a major hurdle in cosmetics. Live bacteria cannot coexist with preservatives or temperature fluctuations, making product formulation extremely difficult.

Postbiotics — delivering the "results" of fermentation directly

Postbiotics are the metabolites produced by microorganisms during fermentation (fermentation filtrates, lysates, etc.). Rather than the bacteria themselves, they deliver the beneficial compounds directly to the skin.

The greatest advantage of postbiotics is their high stability. Since fermentation is already complete, they can coexist with preservatives, withstand temperature changes, and offer greater flexibility in product design.

The Relationship Between Three Biotics Prebiotics Food for beneficial bacteria (inulin, oligosaccharides) Creates a growth-friendly environment Bacteria grow Probiotics Live microorganisms (lactic acid bacteria, yeast, etc.) Stability challenges in cosmetics Bacteria produce Postbiotics Direct supply of fermentation filtrates and metabolites High stability — ideal for cosmetics

Why postbiotics dominate in cosmetics

Cosmetics require preservatives for quality maintenance, but preservatives kill bacteria, making coexistence with live bacteria (probiotics) extremely difficult. Storage temperature management also poses challenges.

Postbiotics, on the other hand, are "just the beneficial compounds that bacteria produced", so there are no preservative compatibility issues, and they deliver stable results. The majority of today's fermented cosmetics use this postbiotic approach.

KAIAN develops skincare products formulated with a 3-strain fermentation complex.
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