Alanine

We confirmed this ingredient's definition and its registered function in public regulatory databases, but found no published study data on how the ingredient itself acts on the skin (checked by KAIAN, September 2026). We will update this page if new reports appear.

An amino acid formulated to moisturize and condition the skin. One of the major constituents of the stratum corneum's natural moisturizing factor (NMF)

Reported as one of the major constituents of NMF in in vivo measurements of human stratum corneum (confocal Raman spectroscopy). No human study directly showing a moisturizing effect of topically applied alanine alone was confirmed (uptake into isolated corneocytes has been reported in vitro)

No public data on typical concentrations in cosmetics could be confirmed (varies by product)

No public data on the time to a perceptible effect with topical use could be confirmed

Ingredient-specific irritation data not confirmed. The US CIR Expert Panel concluded that α-amino acids are safe as cosmetic ingredients under the practices of use and concentration assessed (2013; whether this ingredient was among those assessed is unconfirmed)